Thrombin Receptor Agonist Peptide
Tocris Bioscience, part of Bio-Techne | Catalog # 1185
Causes platelet aggregation and secretion
Key Product Details
Description
Causes platelet aggregation and secretion
Alternative Names
TRAP
Product Description
Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 μM) and secretion.Product Specifications
Molecular Weight
1739.95
Formula
C81H118N20O23
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
137339-65-2
PubChem ID
16131180
InChI Key
OXHYRVSBKWIFES-WWSDOYNLSA-N
SMILES
[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.9mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Vassallo Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 1992 PMID: 1313429
- Vu Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991 PMID: 1672265
- Huang 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 1991 PMID: 1655750
Product Specific Notices for Thrombin Receptor Agonist Peptide
For research use only
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