Thalidomide 4'-ether-alkylC4-acid

Tocris Bioscience, part of Bio-Techne | Catalog # 7331

Cereblon ligand with alkyl linker and terminal acid for onward chemistry
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Key Product Details

Description

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

View all Cereblon Ligands plus Linker Building Blocks »

Product Description

Thalidomide 4'-ether-alkylC4-acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with a terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

374.35

Formula

C18H18N2O7

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

5-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]pentanoic acid

CAS Number

2169266-67-3

PubChem ID

132211977

InChI Key

HCUNNTIALPNNPY-UHFFFAOYSA-N

SMILES

OC(CCCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Product Documents for Thalidomide 4'-ether-alkylC4-acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Thalidomide 4'-ether-alkylC4-acid

For research use only

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