tDHU, acid

Tocris Bioscience, part of Bio-Techne | Catalog # 7773

Functionalized cereblon ligand for PROTAC development
Catalog #
Availability
Size / Price
Qty
7773/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Functionalized cereblon ligand for PROTAC development

View all Functionalized E3 Ligand Building Blocks »

Product Description

tDHU, acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a benzoic acid functional handle for ready conjugation to a linker/target protein ligand.

Part of a range of functionalized tool molecules for PROTAC® Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

248.24

Formula

C12H12N2O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-Methyl-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)benzoic acid

CAS Number

2377643-37-1

PubChem ID

139534352

InChI Key

NXRZIUASGSMTJJ-UHFFFAOYSA-N

SMILES

O=C(C1=CC=C(C)C(N2C(NC(CC2)=O)=O)=C1)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for tDHU, acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for tDHU, acid

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.