TC-E 5005

Name: TC-E 5005
Brand: Tocris Bioscience
SKU: 4572
Rating: 4 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4572

(1)

COA / SDS

Potent and selective PDE10A inhibitor

Discontinued Product

4572 has been discontinued. View all Phosphodiesterase Inhibitors products.

Key Product Details

Description:	Potent and selective PDE10A inhibitor
Chemical Name:	2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine
Purity:	≥99% (HPLC)
Molecular Weight:	270.33

View Full Technical Details for TC-E 5005

Technical Data
Citations / Reviews (1)

Biological Activity for TC-E 5005

TC-E 5005 is a potent and selective PDE10A inhibitor (IC₅₀ values are 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively and >5000 nM at PDE1B, 4A, 6, 8A and 9A). Reverses MK 801-induced hyperactivity in vivo.

Technical Data for TC-E 5005

M. Wt	270.33
Formula	C₁₅H₁₈N₄O
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	959705-64-7
PubChem ID	24802717
InChi Key	YNADXFWEXJTQSZ-UHFFFAOYSA-N
Smiles	CC2=NC1=CC=C(OC)N=C1N3C2=C(C)N=C3CCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for TC-E 5005

References are publications that support the biological activity of the product.

Hofgen Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors. J.Med.Chem. 2010 PMID: 20450197

TC-E 5005

Tocris Bioscience, part of Bio-Techne | Catalog # 4572

Key Product Details

Biological Activity for TC-E 5005

Technical Data for TC-E 5005

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for TC-E 5005

Product Documents for TC-E 5005

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注