Talampanel

Tocris Bioscience, part of Bio-Techne | Catalog # 5032

Non-competitive non-NMDA iGluR antagonist
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Key Product Details

Description

Non-competitive non-NMDA iGluR antagonist

Alternative Names

GYKI 53773,LY 300164

View all AMPA Receptor Antagonists »

Product Description

Talampanel is a non-competitive AMPA/kainate receptor antagonist that displays 2.3-3-fold more potent activity than GYKI 52466 (Cat. No. 1454). Potentiates the anticonvulsive activity of antiepileptic drugs in animal models of seizures. Orally active.

Product Specifications

Molecular Weight

337.37

Formula

C19H19N3O3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

CAS Number

161832-65-1

PubChem ID

164509

InChI Key

JACAAXNEHGBPOQ-LLVKDONJSA-N

SMILES

NC(C=C4)=CC=C4C1=NN(C(C)=O)[C@H](C)CC2=C1C=C(OCO3)C3=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.74 100

Preparing Stock Solutions for Talampanel

The following data is based on the product molecular weight 337.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL
10 mM 0.30 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Talampanel

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Talampanel

For research use only

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