STX 64

Tocris Bioscience, part of Bio-Techne | Catalog # 7341

Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II
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Key Product Details

Description

Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II

View all Hydrolase Inhibitors »

Product Description

STX 64 is a potent steroid sulfatase inhibitor (IC50 = 8 nM). Estrone sulfate-stimulated uterine growth and mammary tumor growth are inhibited by STX 64 in animal models. STX 64 shows inhibition of steroid sulfatase activity in peripheral blood lymphocytes, liver and tumor tissues and is active in vivo. STX 64 is also a potent inhibitor of carbonic anhydrase II (IC50 = 25 nM).

Product Specifications

Molecular Weight

309.34

Formula

C14H15NO5S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate

CAS Number

288628-05-7

PubChem ID

5287541

InChI Key

DSLPMJSGSBLWRE-UHFFFAOYSA-N

SMILES

O=C1OC=2C=C(OS(=O)(=O)N)C=CC2C3=C1CCCCC3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.93 100
Ethanol 3.09 10

Preparing Stock Solutions for STX 64

The following data is based on the product molecular weight 309.34

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.23 mL 16.16 mL 32.33 mL
5 mM 0.65 mL 3.23 mL 6.47 mL
10 mM 0.32 mL 1.62 mL 3.23 mL
50 mM 0.06 mL 0.32 mL 0.65 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for STX 64

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for STX 64

For research use only

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