SSR 180711 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5559

Selective α7 nAChR partial agonist
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Key Product Details

Description

Selective α7 nAChR partial agonist

View all Nicotinic (a7) Receptor Agonists »

Product Description

SSR 180711 hydrochloride is a partial agonist at α7 nAChR. Enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. Increases extracellular dopamine levels in rat prefrontal cortex. Also exhibits antidepressant-like properties.

Product Specifications

Molecular Weight

361.66

Formula

C14H17BrN2O2.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride

CAS Number

446031-79-4

PubChem ID

9928899

InChI Key

YNBXNVUZXFMNSJ-UHFFFAOYSA-N

SMILES

O=C(N1C2CCN(CC2)CC1)OC3=CC=C(Br)C=C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 36.17 100
DMSO 36.17 100

Preparing Stock Solutions for SSR 180711 hydrochloride

The following data is based on the product molecular weight 361.66

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.77 mL 13.83 mL 27.65 mL
5 mM 0.55 mL 2.77 mL 5.53 mL
10 mM 0.28 mL 1.38 mL 2.77 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for SSR 180711 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SSR 180711 hydrochloride

For research use only

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