SR 57227 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1205
Potent and selective 5-HT3 agonist
Key Product Details
Description
Potent and selective 5-HT3 agonist
Product Description
SR 57227 hydrochloride is a high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.Product Specifications
Molecular Weight
248.15
Formula
C10H14ClN3.HCl
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride
CAS Number
77145-61-0
PubChem ID
131746
InChI Key
FUMINTAAUJUVMP-UHFFFAOYSA-N
SMILES
Cl.NC1CCN(CC1)C1=NC(Cl)=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 24.82 | 100 | |
| DMSO | 24.82 | 100 |
Preparing Stock Solutions
for SR 57227 hydrochloride
The following data is based on the product molecular weight 248.15
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.03 mL | 20.15 mL | 40.30 mL |
| 5 mM | 0.81 mL | 4.03 mL | 8.06 mL |
| 10 mM | 0.40 mL | 2.01 mL | 4.03 mL |
| 50 mM | 0.08 mL | 0.40 mL | 0.81 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Edwards 5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization. Brain Res. 1996 PMID: 8891244
- Bachy SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo. Eur.J.Pharmacol. 1993 PMID: 7689975
Product Specific Notices for SR 57227 hydrochloride
For research use only
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