SNAP
Tocris Bioscience, part of Bio-Techne | Catalog # 0598
A stable analog of endogenous S-nitroso compounds
Key Product Details
Description
A stable analog of endogenous S-nitroso compounds
Product Description
SNAP is a stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t½ of 37h.Product Specifications
Molecular Weight
220.24
Formula
C7H12N2O4S
Storage
Store at -20°C
Chemical Name
(S)-Nitroso-N-acetylpenicillamine
CAS Number
79032-48-7
PubChem ID
5231
InChI Key
ZIIQCSMRQKCOCT-UHFFFAOYSA-N
SMILES
O=NSC(C)(C)C(NC(C)=O)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.02 | 100 |
Preparing Stock Solutions
for SNAP
The following data is based on the product molecular weight 220.24
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.54 mL | 22.70 mL | 45.41 mL |
| 5 mM | 0.91 mL | 4.54 mL | 9.08 mL |
| 10 mM | 0.45 mL | 2.27 mL | 4.54 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.91 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ferrero Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: correlation with nitric oxide production. Br.J.Pharmacol. 1999 PMID: 10401570
- Cross Neurotoxicity in conscious rats following intraventricular SNAP, a nitric oxide donor. Neuropharmacology 1994 PMID: 7969812
- Ekblad and Sundler Motor responses in rat ileum evoked by nitric oxide donors vs. field stimulation: modulation by pituitary adenylate cyclase-activating peptide, forskolin and guanylate cyclase inhibitors. J.Pharmacol.Exp.Ther. 1997 PMID: 9336304
- Bauer and Fung Differential thermodynamic effects and tolerance properties of nitrogly. and S-nitrosothiol in experimental heart failure. J.Pharmacol.Exp.Ther. 1991 PMID: 1899118
Product Specific Notices for SNAP
For research use only
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