SKF 97541

Tocris Bioscience, part of Bio-Techne | Catalog # 0379

Highly potent GABAB agonist; also GABAA-ρ antagonist
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Key Product Details

Description

Highly potent GABAB agonist; also GABAA-ρ antagonist

Alternative Names

CGP 35024

View all GABA-B Receptor Agonists »

Product Description

SKF 97541 is a potent GABAB agonist (EC50 = 50 nM). SKF 97541 depresses striatal synaptic potentials and hyperpolarizes nigral neurons (EC50 values = 92 nM and 150 nM, respectively). SKF 97541 shows antidepressant effects in animal models and is also a GABAA-ρ antagonist.

Product Specifications

Molecular Weight

137.12

Formula

C4H12NO2P

Storage

Desiccate at RT

Chemical Name

3-Aminopropyl(methyl)phosphinic acid

CAS Number

127729-35-5

PubChem ID

5230

InChI Key

NHVRIDDXGZPJTJ-UHFFFAOYSA-N

SMILES

NCCCP(O)(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 13.71 100

Preparing Stock Solutions for SKF 97541

The following data is based on the product molecular weight 137.12

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 7.29 mL 36.46 mL 72.93 mL
5 mM 1.46 mL 7.29 mL 14.59 mL
10 mM 0.73 mL 3.65 mL 7.29 mL
50 mM 0.15 mL 0.73 mL 1.46 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for SKF 97541

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SKF 97541

For research use only

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