SCH 50911

Tocris Bioscience, part of Bio-Techne | Catalog # 0984

Selective and competitive GABAB antagonist; orally bioavailable
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Key Product Details

Description

Selective and competitive GABAB antagonist; orally bioavailable

View all GABA-B Receptor Antagonists »

Product Description

SCH 50911 is a selective, competitive and orally active GABAB antagonist. Displays an IC50 of 1.1 μM at GABAB, approximately 60 times that of CGP 35348 (Cat. No. 1245) and no binding affinity for GABAA at concentrations up to 100 μM.

Licensing Information

Sold with the permission of Schering Plough Corporation

Product Specifications

Molecular Weight

173.21

Formula

C8H15NO3

Storage

Desiccate at -20°C

Purity

≥98%

Chemical Name

(2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid

CAS Number

733717-87-8

PubChem ID

5311429

InChI Key

SEYCKMQSPUVYEF-LURJTMIESA-N

SMILES

[H][C@]1(CC(O)=O)CNC(C)(C)CO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 17.32 100
phosphate buffered saline 17.32 100

Preparing Stock Solutions for SCH 50911

The following data is based on the product molecular weight 173.21

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.77 mL 28.87 mL 57.73 mL
5 mM 1.15 mL 5.77 mL 11.55 mL
10 mM 0.58 mL 2.89 mL 5.77 mL
50 mM 0.12 mL 0.58 mL 1.15 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for SCH 50911

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SCH 50911

For research use only

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