SB 205384

Tocris Bioscience, part of Bio-Techne | Catalog # 1512

GABAA modulator; slows current decay
Discontinued Product
1512 has been discontinued. View all GABA-A Receptor Modulators products.

Key Product Details

Description

GABAA modulator; slows current decay

View all GABA-A Receptor Modulators »

Product Description

SB 205384 is a GABAA receptor modulator; slows current decay. Potentiates α6, α3 and α5-subunit-containing receptors (EC50 values are 280, 695 and 730 nM respectively). Displays little effect on receptors containing α1 or α2 subunits.

Product Specifications

Molecular Weight

330.40

Formula

C17H18N2O3S

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-[1H]benzothieno[2,3-b]pyridine-3-carboxylic acid 2-butynyl ester

CAS Number

160296-13-9

PubChem ID

197690

InChI Key

JDTZAGLGBRRCJT-UHFFFAOYSA-N

SMILES

CC#CCOC(=O)C1=C(C)N=C2SC3=C(CCC(O)C3)C2=C1N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 33.04 100
DMSO 16.52 50

Preparing Stock Solutions for SB 205384

The following data is based on the product molecular weight 330.40

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.03 mL 15.13 mL 30.27 mL
5 mM 0.61 mL 3.03 mL 6.05 mL
10 mM 0.30 mL 1.51 mL 3.03 mL
50 mM 0.06 mL 0.30 mL 0.61 mL

Calculators

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Reconstitution Calculator

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Product Documents for SB 205384

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SB 205384

For research use only

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