SB 204741

Tocris Bioscience, part of Bio-Techne | Catalog # 1372

Potent, selective 5-HT2B antagonist
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Key Product Details

Description

Potent, selective 5-HT2B antagonist

View all 5-HT2B Receptor Antagonists »

Product Description

SB 204741 is a potent and selective 5-HT2B receptor antagonist (pA2 = 7.95). Displays ≥ 135-fold selectivity over 5-HT2C (pKi = 5.82), 5-HT2A (pKi < 5.2), 5-HT1A, 1D, 1E, 5-HT3 and 5-HT4 receptors.

Licensing Information

Sold under license

Product Specifications

Molecular Weight

286.35

Formula

C14H14N4OS

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(1-Methyl-1H-indolyl-5-yl)-N''-(3-methyl-5-isothiazolyl)urea

CAS Number

152239-46-8

PubChem ID

3277600

InChI Key

USFUFHFQWXDVMH-UHFFFAOYSA-N

SMILES

O=C(NC3=CC(C)=NS3)NC1=CC(C=CN2C)=C2C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.64 100
Ethanol 5.73 20

Preparing Stock Solutions for SB 204741

The following data is based on the product molecular weight 286.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.49 mL 17.46 mL 34.92 mL
5 mM 0.70 mL 3.49 mL 6.98 mL
10 mM 0.35 mL 1.75 mL 3.49 mL
50 mM 0.07 mL 0.35 mL 0.70 mL

Calculators

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Reconstitution Calculator

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Product Documents for SB 204741

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SB 204741

For research use only

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