Sakura 6

Name: Sakura 6
Brand: Tocris Bioscience
SKU: 7897

Tocris Bioscience, part of Bio-Techne | Catalog # 7897

COA / SDS

Promoter of SERT and nNOS interaction

Discontinued Product

7897 has been discontinued. View all 5-HT Transporter Inhibitors products.

Key Product Details

Description:	Promoter of SERT and nNOS interaction
Purity:	≥95% (HPLC)
Molecular Weight:	599.73

View Full Technical Details for Sakura 6

Technical Data
Citations

Biological Activity for Sakura 6

Sakura 6 is a synthetic serotonin transporter (SERT)-binding peptide. Promotes interaction of SERT and neuronal nitric oxide synthase, reducing SERT activity and cell surface SERT, increases auto-inhibition, reduces synaptic 5-HT release and reduces firing in the dorsal raphe nucleus. Induces an acute depressive phenotype in a mouse model of depression.

Technical Data for Sakura 6

M. Wt	599.73
Formula	C₃₁H₄₅N₅O₇
Single Letter Sequence	ADWV (Modifications: Ala-1= N-Cyclohexylethyl-Ala)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2490708-79-5
InChi Key	XLTJIDLKXSSWKU-MUSDWVDSSA-N
Smiles	O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](C(C)C)C(O)=O)=O)=O)[C@H](C)NCCC3CCCCC3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Sakura 6

References are publications that support the biological activity of the product.

Sun Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN. Science 2022 PMID: 36302033

Sakura 6

Tocris Bioscience, part of Bio-Techne | Catalog # 7897

Key Product Details

Biological Activity for Sakura 6

Technical Data for Sakura 6

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Sakura 6

Product Documents for Sakura 6

COA

Certificate of Analysis

SDS

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