(S)-(-)-Sulpiride
Tocris Bioscience, part of Bio-Techne | Catalog # 0895
Standard selective D2-like antagonist
Key Product Details
Description
Standard selective D2-like antagonist
Product Description
(S)-(-)-Sulpiride is an active enantiomer. Selective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, 1, ~ 45 and ~ 77 μM at D2, D3, D4, D1 and D5 receptors respectively).Racemate also available.
Product Specifications
Molecular Weight
341.42
Formula
C15H23N3O4S
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
CAS Number
23672-07-3
PubChem ID
688272
InChI Key
BGRJTUBHPOOWDU-NSHDSACASA-N
SMILES
NS(C1=CC(C(NC[C@]2([H])CCCN2CC)=O)=C(OC)C=C1)(=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.14 | 100 | |
| Ethanol | 3.41 | 10 with gentle warming |
Preparing Stock Solutions
for (S)-(-)-Sulpiride
The following data is based on the product molecular weight 341.42
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.93 mL | 14.64 mL | 29.29 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.86 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.93 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.59 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Seeman and Van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
- Seeman and Van Tol DA D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. Eur.J.Pharmacol. 1993 PMID: 8097160
Product Specific Notices for (S)-(-)-Sulpiride
For research use only
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