RuBi-Glutamate
Tocris Bioscience, part of Bio-Techne | Catalog # 3574
Caged glutamate; excited by visible wavelengths
Key Product Details
Description
Caged glutamate; excited by visible wavelengths
Product Description
RuBi-Glutamate is a ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.MNI-caged-L-glutamate (Cat. No. 1490) also available.
Licensing Information
Sold under licence from Columbia UniversityProduct Specifications
Molecular Weight
970.54
Formula
C28H32N5O4PRu.2NaPF6
Storage
Store at -20°C
Chemical Name
(bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt
CAS Number
2417096-44-5
PubChem ID
90488860
InChI Key
SQQVSHWHIPVYSZ-UHFFFAOYSA-L
SMILES
[Na+].[Na+].[Ru++].CP(C)C.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.NC(CCC([O-])=O)C([O-])=O.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CN=C(C=C1)C1=CC=CC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 19.41 | 20 |
Preparing Stock Solutions
for RuBi-Glutamate
The following data is based on the product molecular weight 970.54
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 5.15 mL | 25.76 mL | 51.52 mL |
| 1 mM | 1.03 mL | 5.15 mL | 10.30 mL |
| 2 mM | 0.52 mL | 2.58 mL | 5.15 mL |
| 10 mM | 0.10 mL | 0.52 mL | 1.03 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Salierno A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes. J.Inorg.Biochem. 2010 PMID: 20060592
- Fino RuBi-Glutamate: two-photon and visible-light photoactivation of neurons and dendritic spines. Front.Neural Circuits 2009 PMID: 19506708
Product Specific Notices for RuBi-Glutamate
For research use only
Loading...
Loading...
Loading...