(RS)-Baclofen
Tocris Bioscience, part of Bio-Techne | Catalog # 0417
Selective GABAB agonist
Product Description
(RS)-Baclofen is a selective GABAB receptor agonist. Skeletal muscle relaxant.R-enantiomer also available.
Product Specifications
Molecular Weight
213.66
Formula
C10H12ClNO2
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
(RS)-4-Amino-3-(4-chlorophenyl)butanoic acid
CAS Number
1134-47-0
PubChem ID
2284
InChI Key
KPYSYYIEGFHWSV-UHFFFAOYSA-N
SMILES
OC(CC(CN)C1=CC=C(Cl)C=C1)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 100 |
Preparing Stock Solutions
for (RS)-Baclofen
The following data is based on the product molecular weight 213.66
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.68 mL | 23.40 mL | 46.80 mL |
| 5 mM | 0.94 mL | 4.68 mL | 9.36 mL |
| 10 mM | 0.47 mL | 2.34 mL | 4.68 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.94 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bowery GABAB receptor pharmacology. Annu.Rev.Pharmacol.Toxicol. 1993 PMID: 8388192
- Hill 3H-Baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain. Nature 1981 PMID: 6259535
- Berthelot 3-Thienylaminobutyric acid and 3-furylaminobutyric acids - synthesis and GABAB receptor binding studies. J.Med.Chem. 1991 PMID: 1652022
Product Specific Notices for (RS)-Baclofen
For research use only
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