RS 100329 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1325

Potent, subtype-selective α1A antagonist
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Key Product Details

Description

Potent, subtype-selective α1A antagonist

View all Adrenergic alpha-1 Receptor Antagonists »

Product Description

RS 100329 hydrochloride is a subtype-selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors). Displays 126- and 50-fold selectivity over human α1B and α1D receptors respectively. Active in vivo.

Licensing Information

Sold with the permission of Roche Bioscience

Product Specifications

Molecular Weight

462.89

Formula

C20H25F3N4O3.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

5-Methyl-3-[3-[3-[4-[2-(2,2,2,-trifluroethoxy)phenyl]-1-piperazinyl]propyl]-2,4-(1H,3H)-pyrimidinedione hydrochloride

CAS Number

1215654-26-4

PubChem ID

11340200

InChI Key

CWVABCXVOAVUJL-UHFFFAOYSA-N

SMILES

Cl.CC1=CNC(=O)N(CCCN2CCN(CC2)C2=C(OCC(F)(F)F)C=CC=C2)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for RS 100329 hydrochloride

The following data is based on the product molecular weight 462.89

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.16 mL 10.80 mL 21.60 mL
5 mM 0.43 mL 2.16 mL 4.32 mL
10 mM 0.22 mL 1.08 mL 2.16 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for RS 100329 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RS 100329 hydrochloride

For research use only

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