RO 5263397 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 6833

Potent TA1 receptor agonist
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Key Product Details

Description

Potent TA1 receptor agonist

View all Trace Amine 1 (TA1) Receptor Agonists »

Product Description

RO 5263397 hydrochloride is a potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice.

Product Specifications

Molecular Weight

230.67

Formula

C10H11FN2O.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(4S)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamine hydrochloride

InChI Key

JFAYMXKBMDRFHY-SBSPUUFOSA-N

SMILES

CC1=C([C@H]2COC(N)=N2)C=CC=C1F.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 23.07 100
DMSO 23.07 100

Preparing Stock Solutions for RO 5263397 hydrochloride

The following data is based on the product molecular weight 230.67

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.34 mL 21.68 mL 43.35 mL
5 mM 0.87 mL 4.34 mL 8.67 mL
10 mM 0.43 mL 2.17 mL 4.34 mL
50 mM 0.09 mL 0.43 mL 0.87 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for RO 5263397 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RO 5263397 hydrochloride

For research use only

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