Ro 10-5824 dihydrochloride

Name: Ro 10-5824 dihydrochloride
Brand: Tocris Bioscience
SKU: 2329

Tocris Bioscience, part of Bio-Techne | Catalog # 2329

Citations (1)

COA / SDS

Selective D4 partial agonist

Discontinued Product

2329 has been discontinued. View all Dopamine D4 Receptor Agonists products.

Key Product Details

Description:	Selective D₄ partial agonist
Chemical Name:	5-[(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-4-pyrimidinamine dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	353.29

View Full Technical Details for Ro 10-5824 dihydrochloride

Technical Data
Citations

Biological Activity for Ro 10-5824 dihydrochloride

Ro 10-5824 dihydrochloride is a selective dopamine D₄ receptor partial agonist (EC₅₀ = 205 nM) that binds with high affinity (K_i = 5.2 nM). Displays 250-fold selectivity over D₃ receptors and > 1000-fold selectivity over D₂, D₁ and D₅ receptors.

Technical Data for Ro 10-5824 dihydrochloride

M. Wt	353.29
Formula	C₁₇H₂₀N₄.2HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	189744-94-3
PubChem ID	16759174
InChi Key	UZHMRJRDYCRKIZ-UHFFFAOYSA-N
Smiles	Cl.Cl.CC1=NC=C(CN2CCC(=CC2)C2=CC=CC=C2)C(N)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Ro 10-5824 dihydrochloride

References are publications that support the biological activity of the product.

Powell RO-10-5824 is a selective DA D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology 2003 PMID: 12646284

Ro 10-5824 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2329

Key Product Details

Biological Activity for Ro 10-5824 dihydrochloride

Technical Data for Ro 10-5824 dihydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ro 10-5824 dihydrochloride

Product Documents for Ro 10-5824 dihydrochloride

COA

Certificate of Analysis

SDS

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