Skip to main content

Riluzole hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0768

GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels
Catalog #
Availability
Size / Price
Qty
Loading...
0768/25

Key Product Details

Description

GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels

Product Description

Inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes. Also activates TRPC5 channels. Psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic, anesthetic and neuroprotective properties.

Product Specifications

Molecular Weight

270.66

Formula

C8H5F3N2OS.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-Amino-6-trifluoromethoxybenzothiazole hydrochloride

CAS Number

850608-87-6]

PubChem ID

6419992

InChI Key

QEAOELIJQRYJJS-UHFFFAOYSA-N

SMILES

Cl.NC1=NC2=CC=C(OC(F)(F)F)C=C2S1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 2.71 10 with gentle warming
DMSO 27.07 100

Preparing Stock Solutions for Riluzole hydrochloride

The following data is based on the product molecular weight 270.66

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.69 mL 18.47 mL 36.95 mL
5 mM 0.74 mL 3.69 mL 7.39 mL
10 mM 0.37 mL 1.85 mL 3.69 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Riluzole hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Riluzole hydrochloride

For research use only

Loading...
Loading...