RGDS peptide

Name: RGDS peptide
Brand: Tocris Bioscience
SKU: 3498
Rating: 5 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3498

(2)

Citations (45)

COA / SDS

Integrin binding sequence; inhibits integrin receptor function

Key Product Details

Description:	Integrin binding sequence; inhibits integrin receptor function
Purity:	≥95% (HPLC)
Molecular Weight:	433.42

View Full Technical Details for RGDS peptide

Technical Data
Citations / Reviews (2)

Biological Activity for RGDS peptide

RGDS peptide is an integrin binding sequence that inhibits integrin receptor function. Decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. Promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro.

Technical Data for RGDS peptide

M. Wt	433.42
Formula	C₁₅H₂₇N₇O₈
Single Letter Sequence	RGDS
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	91037-65-9
PubChem ID	107775
InChi Key	NNRFRJQMBSBXGO-CIUDSAMLSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RGDS peptide

Solubility

Soluble to 1mg/ml in water

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References for RGDS peptide

References are publications that support the biological activity of the product.

Moon Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir.Res. 2009 PMID: 19272161
Droppelmann Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to CTGF/CCN2 due to an increase in the levels of endogenous fibronectin. J.Biol.Chem. 2009 PMID: 19276073
Grigoriou Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. J.Biol.Chem. 2005 PMID: 15522882