Remoxipride hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0916

Selective D2-like antagonist
Discontinued Product
0916 has been discontinued. View all Non-selective Dopamine Receptor Antagonists products.

Key Product Details

Description

Selective D2-like antagonist

View all Non-selective Dopamine Receptor Antagonists »

Product Description

Remoxipride hydrochloride is a dopamine D2 receptor antagonist showing selectivity over D3 and D4 receptors (Ki values are ~ 300, ~ 1600, and ~ 2800 nM for D2, D3 and D4 receptors respectively). Exhibits antipsychotic activity in vivo with no extrapyramidal side effects. 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat.

Product Specifications

Molecular Weight

407.73

Formula

C16H23BrN2O3.HCl

Storage

Store at RT

Chemical Name

(S)-(-)-3-Bromo-N-[(1-ethyl-2-pyrrolidinylmethyl]2,6-dimethoxybenzamide hydrochloride

CAS Number

73220-03-8

PubChem ID

15565709

InChI Key

WCPXLMIPGMFZMY-MERQFXBCSA-N

SMILES

BrC1=CC=C(OC)C(C(NC[C@@]2(CCCN2CC)[H])=O)=C1OC.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for Remoxipride hydrochloride

The following data is based on the product molecular weight 407.73

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.45 mL 12.26 mL 24.53 mL
5 mM 0.49 mL 2.45 mL 4.91 mL
10 mM 0.25 mL 1.23 mL 2.45 mL
50 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Remoxipride hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Remoxipride hydrochloride

For research use only

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