Raclopride

Tocris Bioscience, part of Bio-Techne | Catalog # 1810

Potent and selective D2 and D3 antagonist
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Key Product Details

Description

Potent and selective D2 and D3 antagonist

View all Non-selective Dopamine Receptor Antagonists »

Product Description

Raclopride is a selective and potent dopamine D2/D3 receptor antagonist (Ki values are 1.8, 3.5, 2400 and 18000 nM for D2, D3, D4 and D1 receptors respectively). Centrally active following systemic administration in vivo.

Product Specifications

Molecular Weight

347.24

Formula

C15H20Cl2N2O3

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide

CAS Number

84225-95-6

PubChem ID

3033769

InChI Key

WAOQONBSWFLFPE-VIFPVBQESA-N

SMILES

ClC1=C(OC)C(C(NC[C@H]2N(CC)CCC2)=O)=C(O)C(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.72 100
Ethanol 8.68 25

Preparing Stock Solutions for Raclopride

The following data is based on the product molecular weight 347.24

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.88 mL 14.40 mL 28.80 mL
5 mM 0.58 mL 2.88 mL 5.76 mL
10 mM 0.29 mL 1.44 mL 2.88 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Raclopride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Raclopride

For research use only

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