(R)-(-)-Apomorphine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2073

Dopamine agonist; non-subtype-selective
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Key Product Details

Description

Dopamine agonist; non-subtype-selective

View all Non-selective Dopamine Receptor Agonists »

Product Description

(R)-(-)-Apomorphine hydrochloride is a prototypical dopamine agonist (pKi values are 6.43, 7.08, 7.59, 8.36 and 7.83 for human recombinant D1, D2L, D3, D4 and D5 receptors respectively). Produces biphasic effects on locomotor activity, and displays anti-Parkinsonian and neuroprotective actions following systemic administration in vivo.

Product Specifications

Molecular Weight

303.79

Formula

C17H17NO2.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

(R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride

CAS Number

314-19-2

PubChem ID

9410

InChI Key

SKYZYDSNJIOXRL-BTQNPOSSSA-N

SMILES

OC1=C2C(C[C@]4([H])C3=C2C=CC=C3CCN4C)=CC=C1O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 13.37 50
DMSO 30.38 100

Preparing Stock Solutions for (R)-(-)-Apomorphine hydrochloride

The following data is based on the product molecular weight 303.79

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.29 mL 16.46 mL 32.92 mL
5 mM 0.66 mL 3.29 mL 6.58 mL
10 mM 0.33 mL 1.65 mL 3.29 mL
50 mM 0.07 mL 0.33 mL 0.66 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (R)-(-)-Apomorphine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (R)-(-)-Apomorphine hydrochloride

For research use only

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