QX 314 bromide

Tocris Bioscience, part of Bio-Techne | Catalog # 1014

Na+ channel blocker
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Key Product Details

Description

Na+ channel blocker

View all Voltage-gated Sodium Channel Blockers »

Product Description

QX 314 bromide is a membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na+ channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.

Product Specifications

Molecular Weight

343.31

Formula

C16H27N2OBr

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide

CAS Number

24003-58-5

PubChem ID

9884487

InChI Key

DLHMKHREUTXMCH-UHFFFAOYSA-N

SMILES

[Br-].CC[N+](CC)(CC)CC(=O)NC1=C(C)C=CC=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for QX 314 bromide

The following data is based on the product molecular weight 343.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.91 mL 14.56 mL 29.13 mL
5 mM 0.58 mL 2.91 mL 5.83 mL
10 mM 0.29 mL 1.46 mL 2.91 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for QX 314 bromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for QX 314 bromide

For research use only

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