Quipazine dimaleate
Tocris Bioscience, part of Bio-Techne | Catalog # 0629
5-HT3 agonist
Product Description
Quipazine dimaleate is a selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes.Product Specifications
Molecular Weight
445.43
Formula
C13H15N3.2C4H4O4
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
2-(1-Piperazinyl)quinoline dimaleate
CAS Number
150323-78-7
PubChem ID
6420043
InChI Key
VAOSOCRJSSWBEQ-SPIKMXEPSA-N
SMILES
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CN(CCN1)C1=NC2=C(C=CC=C2)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 44.54 | 100 |
Preparing Stock Solutions
for Quipazine dimaleate
The following data is based on the product molecular weight 445.43
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.25 mL | 11.23 mL | 22.45 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.49 mL |
| 10 mM | 0.22 mL | 1.12 mL | 2.25 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.45 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Peroutka and Hamik [3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes. Eur.J.Pharmacol. 1988 PMID: 3378579
- Sharif Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br.J.Pharmacol. 1991 PMID: 1830236
- Ireland and Tyers Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 1987 PMID: 3814920
Product Specific Notices for Quipazine dimaleate
For research use only
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