PU 23

Name: PU 23
Brand: Tocris Bioscience
SKU: 6885

Tocris Bioscience, part of Bio-Techne | Catalog # 6885

Citations (1)

COA / SDS

Multidrug resistance protein (MRP) 4 inhibitor

Discontinued Product

6885 has been discontinued. View all Multidrug Transporter Inhibitors products.

Key Product Details

Description:	Multidrug resistance protein (MRP) 4 inhibitor
Chemical Name:	N-[[[4-[[(Phenylmethyl)amino]sulfonyl]phenyl]amino]thioxomethyl]benzamide
Purity:	≥98% (HPLC)
Molecular Weight:	425.52

View Full Technical Details for PU 23

Technical Data
Citations

Biological Activity for PU 23

PU 23 is a multidrug resistance protein (MRP) 4 inhibitor. Sensitizes MRP4-overexpressing cells to the anticancer agent 6-Mercaptopurine (Cat. No. 4103; 6-MP) (IC₅₀ values are 14.11 and 6.06 μM in the absence and presence of compound, respectively). Increases accumulation of 6-MP in MRP4-overexpressing cells.

Technical Data for PU 23

M. Wt	425.52
Formula	C₂₁H₁₉N₃O₃S₂
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	817635-93-1
PubChem ID	4779049
InChi Key	RYIRRFWVFHEXTH-UHFFFAOYSA-N
Smiles	O=C(NC(=S)NC1=CC=C(C=C1)[S](=O)(=O)NCC1=CC=CC=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PU 23

References are publications that support the biological activity of the product.

Chen Discovery of novel multidrug resistance protein 4 (MRP4) inhibitors as active agents reducing resistance to anticancer drug 6-Mercaptopurine (6-MP) by structure and ligand-based virtual screening. PLoS One 2018 PMID: 30321196

PU 23

Tocris Bioscience, part of Bio-Techne | Catalog # 6885

Key Product Details

Biological Activity for PU 23

Technical Data for PU 23

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PU 23

Product Documents for PU 23

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

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