PSNCBAM-1

Tocris Bioscience, part of Bio-Techne | Catalog # 5321

Negative allosteric modulator of CB1 receptors
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Key Product Details

Description

Negative allosteric modulator of CB1 receptors

View all Cannabinoid R1/CB1 Modulators »

Product Description

PSNCBAM-1 is a CB1 receptor negative allosteric modulator (IC50 values are 45 and 209 nM for the inhibition of CP 55,940 and WIN 55,212-2 respectively). Has no effect at the CB2 receptor. Decreases food intake and body weight in rats.

Product Specifications

Molecular Weight

392.88

Formula

C22H21ClN4O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-(4-Chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]urea

CAS Number

877202-74-9

PubChem ID

11560249

InChI Key

HDAYFSFWIPRJSO-UHFFFAOYSA-N

SMILES

ClC1=CC=C(NC(NC2=CC(C3=CC=CC(N4CCCC4)=N3)=CC=C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.29 100

Preparing Stock Solutions for PSNCBAM-1

The following data is based on the product molecular weight 392.88

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.55 mL 12.73 mL 25.45 mL
5 mM 0.51 mL 2.55 mL 5.09 mL
10 mM 0.25 mL 1.27 mL 2.55 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Product Documents for PSNCBAM-1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PSNCBAM-1

For research use only

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