Prostaglandin F2α
Tocris Bioscience, part of Bio-Techne | Catalog # 4214
Naturally-occurring prostanoid; potent vasoconstrictor
Key Product Details
Description
Naturally-occurring prostanoid; potent vasoconstrictor
Product Description
Prostaglandin F2α is a prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.Product Specifications
Molecular Weight
475.62
Formula
C20H34O5.C4H11NO3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
CAS Number
38562-01-5
PubChem ID
5282415
InChI Key
IYGXEHDCSOYNKY-RZHHZEQLSA-N
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 47.56 | 100 | |
| Ethanol | 47.56 | 100 |
Preparing Stock Solutions
for Prostaglandin F2α
The following data is based on the product molecular weight 475.62
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.10 mL | 10.51 mL | 21.03 mL |
| 5 mM | 0.42 mL | 2.10 mL | 4.21 mL |
| 10 mM | 0.21 mL | 1.05 mL | 2.10 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.42 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Girsh and Dekel Involvement of endothelin-1 and its receptors in PGF2α-induced luteolysis in the rat. Mol.Reprod.Dev. 2002 PMID: 12211063
- Lai Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol.
- Samuelsson Prostaglandins and throboxanes. Annu.Rev.Biochem. 1978 PMID: 209733
Product Specific Notices for Prostaglandin F2α
For research use only
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