pp60 c-src (521-533) (phosphorylated)

Name: pp60 c-src (521-533) (phosphorylated)
Brand: Tocris Bioscience
SKU: 1923

Tocris Bioscience, part of Bio-Techne | Catalog # 1923

COA / SDS

Inhibits tyrosine kinase activity of pp60c-src and pp60v-src

Discontinued Product

1923 has been discontinued. View all Src Family Kinase Inhibitors products.

Key Product Details

Description:	Inhibits tyrosine kinase activity of pp60^c-src and pp60^v-src
Molecular Weight:	1543.5

View Full Technical Details for pp60 c-src (521-533) (phosphorylated)

Technical Data
Citations

Biological Activity for pp60 c-src (521-533) (phosphorylated)

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60^c-src carboxy terminal regulatory domain; phosphorylated at Tyr⁵²⁷. Binds to pp60^c-src and pp60^v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.

Technical Data for pp60 c-src (521-533) (phosphorylated)

M. Wt	1543.5
Formula	C₆₂H₉₅N₁₆O₂₈P
Single Letter Sequence	TSTEPQYQPGENL (Modifications: Tyr-7 = pTyr)
Storage	Store at -20°C
CAS Number	149299-77-4
PubChem ID	16137939
InChi Key	QTTDEIYNMOIHBO-VVTMTNTLSA-N
Smiles	[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for pp60 c-src (521-533) (phosphorylated)

References are publications that support the biological activity of the product.

Roussel Selective binding of activated pp60^c-src by an immobilized synthetic phosphopeptide modeled on the carboxy terminus of pp60^c-src. Proc.Natl.Acad.Sci.U.S.A. 1991 PMID: 1720546
Harder Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. Biochem.J. 1994 PMID: 8135747

pp60 c-src (521-533) (phosphorylated)

Tocris Bioscience, part of Bio-Techne | Catalog # 1923

Key Product Details

Biological Activity for pp60 c-src (521-533) (phosphorylated)

Technical Data for pp60 c-src (521-533) (phosphorylated)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for pp60 c-src (521-533) (phosphorylated)

Product Documents for pp60 c-src (521-533) (phosphorylated)

COA

Certificate of Analysis

SDS

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