Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
Tocris Bioscience, part of Bio-Techne | Catalog # 7471
Cereblon ligand with terminal piperidine for onward chemistry
Key Product Details
Description
Cereblon ligand with terminal piperidine for onward chemistry
Product Description
Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal piperidine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC® Degrader R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
530.42
Formula
C23H28FN5O4.2HCl
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-6-[4-(4-piperidinylmethyl)-1-piperazinyl]-1H-isoindole-1,3(2H)-dione dihydrochloride
CAS Number
2758431-94-4
InChI Key
RPBQFDUBJGNGHE-UHFFFAOYSA-N
SMILES
FC1=C(N2CCN(CC2)CC3CCNCC3)C=C4C(N(C(C4=C1)=O)C5CCC(NC5=O)=O)=O.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
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Product Specific Notices for Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
For research use only
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