(+)-PD 128907 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1243
High affinity D3 agonist (D3 ≥ D2 > D4)
Key Product Details
Description
High affinity D3 agonist (D3 ≥ D2 > D4)
Product Description
(+)-PD 128907 hydrochloride is a high affinity D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.Product Specifications
Molecular Weight
285.77
Formula
C14H19NO3.HCl
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
(4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride
CAS Number
300576-59-4
PubChem ID
11957668
InChI Key
DCFXOTRONMKUJB-QMDUSEKHSA-N
SMILES
CCCN3[C@@H]2COC1=CC=C(O)C=C1[C@H]2OCC3.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 2.86 | 10 |
Preparing Stock Solutions
for (+)-PD 128907 hydrochloride
The following data is based on the product molecular weight 285.77
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.99 mL | 174.97 mL | 349.93 mL |
| 0.5 mM | 7.00 mL | 34.99 mL | 69.99 mL |
| 1 mM | 3.50 mL | 17.50 mL | 34.99 mL |
| 5 mM | 0.70 mL | 3.50 mL | 7.00 mL |
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Pugsley Neurochemical and functional characterization of the preferentially selective DA D3 agonist PD 128907. J.Pharmacol.Exp.Ther. 1995 PMID: 8531103
- Witkin Atypical antipsychotic-like effects of the DA D3 receptor agonist (+)-PD 128907. Eur.J.Pharmacol. 1998 PMID: 9741997
- Bristow The behavioural and neurochemical profile of the putative DA D3 receptor agonist, (+)-PD 128907, in the rat. Neuropharmacology 1996 PMID: 8783203
Product Specific Notices for (+)-PD 128907 hydrochloride
For research use only
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