(+)-JQ1 bump-N, acid functionalized
Tocris Bioscience, part of Bio-Techne | Catalog # 8827
Negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689)
Key Product Details
Description
Negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689)
Product Description
(+)-JQ1 bump-N, acid functionalized is a negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689).Product Specifications
Molecular Weight
428.94
Formula
C21H21ClN4O2S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(S)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
InChI Key
UAFUXHFSKWIFOW-YJBOKZPZSA-N
SMILES
CC1=C(C)C(C(C2=CC=C(C=C2)Cl)=N[C@@H]([C@@H](C(O)=O)CC)C3=NN=C(C)N43)=C4S1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 42.89 | 100 |
Preparing Stock Solutions
for (+)-JQ1 bump-N, acid functionalized
The following data is based on the product molecular weight 428.94
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.33 mL | 11.66 mL | 23.31 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
| 10 mM | 0.23 mL | 1.17 mL | 2.33 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.47 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bond Development of BromoTag: a "Bump-and-Hole"-PROTAC system to induce potent, rapid, and selective degradation of tagged target proteins. J.Med.Chem. 2021 PMID: 34652918
Product Specific Notices for (+)-JQ1 bump-N, acid functionalized
For research use only
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