PKI (5-24)
Tocris Bioscience, part of Bio-Techne | Catalog # 6221
High affinity PKA inhibitor
Product Description
PKI (5-24) is a high affinity PKA inhibitor (Ki = 2.3 nM).Product Specifications
Molecular Weight
2222.40
Formula
C94H148N32O31
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
99534-03-9
PubChem ID
102397230
InChI Key
AXOXZJJMUVSZQY-LGGJAOENSA-N
SMILES
[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Narayana Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine. Biochemistry 1997 PMID: 9109651
- Cheng A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J.Biol.Chem. 1986 PMID: 3511044
Product Specific Notices for PKI (5-24)
For research use only
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