Physostigmine hemisulfate

Name: Physostigmine hemisulfate
Brand: Tocris Bioscience
SKU: 0622

Tocris Bioscience, part of Bio-Techne | Catalog # 0622

Citations (22)

COA / SDS

Cholinesterase inhibitor

Key Product Details

Description:	Cholinesterase inhibitor
Chemical Name:	(3aS)-cis-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate
Purity:	≥98% (HPLC)
Molecular Weight:	324.39

View Full Technical Details for Physostigmine hemisulfate

Technical Data
Citations

Biological Activity for Physostigmine hemisulfate

Physostigmine hemisulfate is a cholinesterase inhibitor.

Technical Data for Physostigmine hemisulfate

M. Wt	324.39
Formula	C₁₅H₂₁N₃O₂.½H₂SO₄
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	64-47-1
PubChem ID	21872909
InChi Key	YYBNDIVPHIWTPK-UHFFFAOYSA-N
Smiles	OS(O)(=O)=O.CNC(=O)OC1=CC=C2N(C)C3N(C)CCC3(C)C2=C1.CNC(=O)OC1=CC=C2N(C)C3N(C)CCC3(C)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Physostigmine hemisulfate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	32.44	100

Preparing Stock Solutions for Physostigmine hemisulfate

The following data is based on the product molecular weight 324.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.08 mL	15.41 mL	30.83 mL
5 mM	0.62 mL	3.08 mL	6.17 mL
10 mM	0.31 mL	1.54 mL	3.08 mL
50 mM	0.06 mL	0.31 mL	0.62 mL

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Reconstitution Calculator

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References for Physostigmine hemisulfate

References are publications that support the biological activity of the product.

Millard and Broomfield Anticholinesterases: medical applications of neurochemical principles. J.Neurochem 1995 PMID: 7722478