Phenyl-glutarimide 4'-oxyacetic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 7670

Functionalized cereblon ligand for PROTAC development
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Key Product Details

Description

Functionalized cereblon ligand for PROTAC development

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Product Description

Phenyl-glutarimide 4'-oxyacetic acid is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PG-PROTACs that exhibit improved stability to hydrolysis and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

263.25

Formula

C13H13NO5

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2-(4-(2,6-Dioxopiperidin-3-yl)phenoxy)acetic acid

CAS Number

2782024-58-0

InChI Key

AJINEEJVZAYBCQ-UHFFFAOYSA-N

SMILES

O=C(N1)CCC(C2=CC=C(C=C2)OCC(O)=O)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Phenyl-glutarimide 4'-oxyacetic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Phenyl-glutarimide 4'-oxyacetic acid

For research use only

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