Perhexiline maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 5166
Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor
Key Product Details
Description
Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor
Product Description
Perhexiline maleate is a carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor. Inhibits palmitate oxidation in rat cardiomyocytes and increases cardiac efficiency in isolated rat hearts. Antianginal.Product Specifications
Molecular Weight
393.56
Formula
C19H35N.C4H4O4
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-(2,2-Dicyclohexylethyl)piperidine maleate
CAS Number
6724-53-4
PubChem ID
5284439
InChI Key
JDZOTSLZMQDFLG-BTJKTKAUSA-N
SMILES
OC(\C=C/C(O)=O)=O.C1(CC(C3CCCCC3)C2CCCCC2)NCCCC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.36 | 100 | |
| Ethanol | 7.87 | 20 |
Preparing Stock Solutions
for Perhexiline maleate
The following data is based on the product molecular weight 393.56
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.54 mL | 12.70 mL | 25.41 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
| 10 mM | 0.25 mL | 1.27 mL | 2.54 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.51 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Unger Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. J.Cardiovasc.Pharmacol. 2005 PMID: 16306812
- Yin Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. J.Mol.Cell.Cardiol. 2013 PMID: 23277191
- Kennedy Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiod. Biochem.Pharmacol. 1996 PMID: 8694852
Product Specific Notices for Perhexiline maleate
For research use only
Loading...
Loading...
Loading...