PDD 00017272
Tocris Bioscience, part of Bio-Techne | Catalog # 7006
Potent PARG inhibitor
Product Description
PDD 00017272 is a potent poly (ADP ribose) glycohydrolase (PARG) inhibitor (IC50 values are 4.8 nM in biochemical assay and 9.2 nM in cell based assay).Licensing Information
Sold under license from Cancer Research Technology Ltd (Ximbio).Product Specifications
Molecular Weight
531.66
Formula
C23H25N5O4S3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide
CAS Number
1945950-20-8
PubChem ID
134169694
InChI Key
QOEXRJYTAZZRPL-UHFFFAOYSA-N
SMILES
CC1=NC=C(S1)CN2C(N(C3=CC=C(S(=O)(NC4(CC4)C)=O)C=C3C2=O)CC5=C(N=C(S5)C)C)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 10.63 | 20 with gentle warming |
Preparing Stock Solutions
for PDD 00017272
The following data is based on the product molecular weight 531.66
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 9.40 mL | 47.02 mL | 94.05 mL |
| 1 mM | 1.88 mL | 9.40 mL | 18.81 mL |
| 2 mM | 0.94 mL | 4.70 mL | 9.40 mL |
| 10 mM | 0.19 mL | 0.94 mL | 1.88 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for PDD 00017272
For research use only
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