PD 90780

Tocris Bioscience, part of Bio-Techne | Catalog # 5101

Inhibits NGF binding to p75NTR
Discontinued Product
5101 has been discontinued. View all Trk Receptor Inhibitors products.

Key Product Details

Description

Inhibits NGF binding to p75NTR

View all Trk Receptor Inhibitors »

Product Description

PD 90780 is a a nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1 μM in CHO cells); binds NGF, not p75NTR. Affinity maybe altered by the presence of TrkA receptors. Neuroprotective.

Product Specifications

Molecular Weight

362.34

Formula

C19H14N4O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid

CAS Number

77422-99-2

PubChem ID

9885305

InChI Key

IAZAGXDMMVWYKF-UHFFFAOYSA-N

SMILES

O=C(C4=CC=CC=C4)NC1=CC=C3C(C(N2C(N3C)=CC(C(O)=O)=N2)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. NaOH 7.25 20 with sonication

Preparing Stock Solutions for PD 90780

The following data is based on the product molecular weight 362.34

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 13.80 mL 69.00 mL 137.99 mL
1 mM 2.76 mL 13.80 mL 27.60 mL
2 mM 1.38 mL 6.90 mL 13.80 mL
10 mM 0.28 mL 1.38 mL 2.76 mL

Calculators

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Reconstitution Calculator

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Product Documents for PD 90780

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PD 90780

For research use only

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