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Pam3CSK4

Tocris Bioscience, part of Bio-Techne | Catalog # 4633

TLR1/2 agonist; induces cytokine production
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4633/1

Key Product Details

Description

TLR1/2 agonist; induces cytokine production

Product Description

Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist; induces production of TNF-α and IL-6 in macrophages. Stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells. Promotes differentiation of naive CD4+ T cells into Th17 cells.

Product Specifications

Molecular Weight

1510.24

Formula

C81H156N10O13S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

112208-00-1

PubChem ID

130704

InChI Key

OEDPHAKKZGDBEV-GFPBKZJXSA-N

SMILES

[H]N([C@@H](CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)CCCCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in 50% Ethanol / water

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Pam3CSK4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pam3CSK4

For research use only

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