Oxcarbazepine
Tocris Bioscience, part of Bio-Techne | Catalog # 3864
Anticonvulsant; inhibits Na+ channel activity
Key Product Details
Description
Anticonvulsant; inhibits Na+ channel activity
Product Description
Oxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.Product Specifications
Molecular Weight
252.27
Formula
C15H12N2O2
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
CAS Number
28721-07-5
PubChem ID
34312
InChI Key
CTRLABGOLIVAIY-UHFFFAOYSA-N
SMILES
NC(N(C(C=CC=C3)=C3C2)C1=CC=CC=C1C2=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 12.61 | 50 |
Preparing Stock Solutions
for Oxcarbazepine
The following data is based on the product molecular weight 252.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 7.93 mL | 39.64 mL | 79.28 mL |
| 2.5 mM | 1.59 mL | 7.93 mL | 15.86 mL |
| 5 mM | 0.79 mL | 3.96 mL | 7.93 mL |
| 25 mM | 0.16 mL | 0.79 mL | 1.59 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ambrosio Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem.Res. 2002 PMID: 11926264
- Zheng Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures. Epilepsia 2009 PMID: 18717705
- Schmutz Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action. Epilepsia 1994 PMID: 8039471
Product Specific Notices for Oxcarbazepine
For research use only
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