OXA (17-33)

Name: OXA (17-33)
Brand: Tocris Bioscience
SKU: 5115

Tocris Bioscience, part of Bio-Techne | Catalog # 5115

Citations (1)

COA / SDS

Potent and selective peptide OX1 agonist

Key Product Details

Description:	Potent and selective peptide OX₁ agonist
Purity:	≥95% (HPLC)
Molecular Weight:	1749

View Full Technical Details for OXA (17-33)

Technical Data
Citations

Biological Activity for OXA (17-33)

OXA (17-33) is a potent and selective peptide orexin OX₁ receptor agonist (EC₅₀ values are 8.29 and 187 nM for OX₁ and OX₂ receptors respectively). Truncated form of orexin A (Cat. No. 1455).

Technical Data for OXA (17-33)

M. Wt	1749
Formula	C₇₉H₁₂₅N₂₃O₂₂
Single Letter Sequence	YELLHGAGNHAAGILTL (Modifications: Leu-33 = C-terminal amide)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	343268-91-7
PubChem ID	44376806
InChi Key	JPRBZUXULYLVPJ-HYNYKCRDSA-N
Smiles	[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for OXA (17-33)

Solubility

Soluble to 1mg/ml in water

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References for OXA (17-33)

References are publications that support the biological activity of the product.

German Truncated orexin peptides: structure-activity relationship studies. Med.Chem.Lett. 2013 PMID: 24707347
Darker Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. Bioorg.Med.Chem.Lett. 2001 PMID: 11266181