Ovalbumin peptide (257-264) New

Name: Ovalbumin peptide (257-264)
Brand: Tocris Bioscience
SKU: 7790

Tocris Bioscience, part of Bio-Techne | Catalog # 7790

COA / SDS

Immunogenic glycoprotein used as model antigen for immunization and vaccination research.

Key Product Details

Description:	Immunogenic glycoprotein used as model antigen for immunization and vaccination research.
Alternative Names:	OVA peptide
Purity:	≥95% (HPLC)
Molecular Weight:	963.13

View Full Technical Details for Ovalbumin peptide (257-264)

Technical Data
Citations

Biological Activity for Ovalbumin peptide (257-264)

Ovalbumin peptide (257-264) is an immunogenic glycoprotein used as model antigen for immunization and vaccination research and to investigate antigen presentation and T cell activation. This peptide plays a critical role in cancer studies, serving as a key agent to evaluate macrophage antigen presentation and to drive robust CD8+ T cell proliferation. Used in multiple cancer models, including oral squamous cell carcinoma, breast cancer, glioblastoma, triple-negative breast cancer, esophageal squamous cell carcinoma, and B-cell malignancies. Used for investigation into immune response dynamics, cytotoxic T cell activity, tumor microenvironment interactions, and immune evasion mechanisms.

Technical Data for Ovalbumin peptide (257-264)

M. Wt	963.13
Formula	C₄₅H₇₄N₁₀O₁₃
Single Letter Sequence	SIINFEKL
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	138831-86-4
PubChem ID	447764
InChi Key	JVJGCCBAOOWGEO-RUTPOYCXSA-N
Smiles	O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ovalbumin peptide (257-264)

Solubility

Soluble to 1mg/ml in water

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References for Ovalbumin peptide (257-264)

References are publications that support the biological activity of the product.

Ritter ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack. Science 2022 PMID: 35446649
Dong Poria cocos polysaccharide induced Th1-type immune responses to ovalbumin in mice. PLOS One 2021 PMID: 33411807
Jaeger Deciphering the immunopeptidome in vivo reveals new tumour antigens. Nature 2022 PMID: 35705813
Li Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature 2023 PMID: 37344599
Booty Microfluidic squeezing enables MHC class I antigen presentation by diverse immune cells to elicit CD8+ T cell responses with antitumor activity. J.Immunol. 2022 PMID: 35091434