Oligomycin A
Tocris Bioscience, part of Bio-Techne | Catalog # 4110
Inhibitor of mitochondrial ATPase
Key Product Details
Description
Inhibitor of mitochondrial ATPase
Product Description
Oligomycin A is an inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.Product Specifications
Molecular Weight
791.06
Formula
C45H74O11
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione
CAS Number
579-13-5
PubChem ID
5281899
InChI Key
MNULEGDCPYONBU-WMBHJXFZSA-N
SMILES
CC[C@](CC[C@@]([H])(O[C@@]2(CC[C@@H](C)[C@@]([H])(C[C@@H](O)C)O2)[C@@H]1C)[C@H](C)[C@]1([H])OC(/C=C/[C@H]([C@@H]([C@@H](C)C([C@@H](C)[C@H](O)[C@H]3C)=O)O)C)=O)([H])/C=C/C=C/C[C@H](C)[C@@H](O)[C@](C)(O)C3=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| Ethanol | 7.91 | 10 |
Preparing Stock Solutions
for Oligomycin A
The following data is based on the product molecular weight 791.06
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.64 mL | 63.21 mL | 126.41 mL |
| 0.5 mM | 2.53 mL | 12.64 mL | 25.28 mL |
| 1 mM | 1.26 mL | 6.32 mL | 12.64 mL |
| 5 mM | 0.25 mL | 1.26 mL | 2.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Salomon Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem.Biol. 2001 PMID: 11182320
Product Specific Notices for Oligomycin A
For research use only
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