Oleamide

Name: Oleamide
Brand: Tocris Bioscience
SKU: 0878

Tocris Bioscience, part of Bio-Techne | Catalog # 0878

COA / SDS

Sleep-inducing brain lipid

Discontinued Product

0878 has been discontinued. View all Additional 5-HT-Related Compounds products.

Key Product Details

Description:	Sleep-inducing brain lipid
Chemical Name:	cis-9-Octadecenamide
Purity:	≥98%
Molecular Weight:	281.48

View Full Technical Details for Oleamide

Technical Data
Citations

Biological Activity for Oleamide

Oleamide is an endogenous sleep-inducing lipid. Acts as an agonist at the CB₁ cannabinoid receptor (EC₅₀ = 1.64 μM). Also appears to potentiate the actions of 5-HT on 5-HT_2A and _2C receptors, and act via an allosteric regulatory site on 5-HT₇ receptors.

Technical Data for Oleamide

M. Wt	281.48
Formula	C₁₈H₃₅NO
Storage	Store at +4°C
Purity	≥98%
CAS Number	301-02-0
PubChem ID	5283387
InChi Key	FATBGEAMYMYZAF-KTKRTIGZSA-N
Smiles	CCCCCCCC\C=C/CCCCCCCC(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Oleamide

References are publications that support the biological activity of the product.

Leggett Oleamide is a selective endogenous agonist of rat and human CB₁ cannabinoid receptors. Br.J.Pharmacol. 2004 PMID: 14707029
Hedlund Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine₇ receptors. Biochem.Pharmacol. 1999 PMID: 10571256
Huidobro-Toro and Harris Brain lipids that induce sleep are novel modulators of 5-hydroxytryptamine receptors. Proc.Natl.Acad.Sci.U.S.A. 1996 PMID: 8755606
Cravatt Chemical characterisation of a family of brain lipids that induces sleep. Science 1995 PMID: 7770779

Oleamide

Tocris Bioscience, part of Bio-Techne | Catalog # 0878

Key Product Details

Biological Activity for Oleamide

Technical Data for Oleamide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Oleamide

Product Documents for Oleamide

COA

Certificate of Analysis

SDS

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