NU 9056
Tocris Bioscience, part of Bio-Techne | Catalog # 4903
Inhibitor of KAT5 (Tip60)
Key Product Details
Description
Inhibitor of KAT5 (Tip60)
Product Description
NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.Product Specifications
Molecular Weight
232.37
Formula
C6H4N2S4
Storage
Store at -20°C
Chemical Name
5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole
CAS Number
1450644-28-6
PubChem ID
72201043
InChI Key
MLRAMCAHIWHWRM-UHFFFAOYSA-N
SMILES
C1(SSC2=CC=NS2)=CC=NS1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml) |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Coffey Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One 2012 PMID: 23056207
Product Specific Notices for NU 9056
For research use only
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