[Nle4,D-Phe7]-α-MSH
Tocris Bioscience, part of Bio-Techne | Catalog # 3013
Melanocortin receptor agonist
Key Product Details
Description
Melanocortin receptor agonist
Alternative Names
Melanotan I,MT-I,NDP-α-MSH
Product Description
[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-MSH that is an agonist at melanocortin receptors (Ki values are 0.085, 0.4, 3.8 and 5.1 nM for MC1, MC3, MC4 and MC5 receptors respectively).Product Specifications
Molecular Weight
1646.86
Formula
C78H111N21O19
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
75921-69-6
PubChem ID
16132139
InChI Key
UAHFGYDRQSXQEB-PWPYQVNISA-N
SMILES
CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.6mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sawyer 4-Norleucine, 7-D-phenylalanine-α-melanocyte-stimulating hormone: a highly potent α-melanotropin with ultrapotent biological activity. Proc.Natl.Acad.Sci.USA
- Wikber Melanocortin receptors: perspectives for novel drugs. Eur.J.Pharmacol. 1999 PMID: 10443584
Product Specific Notices
For research use only
Loading...
Loading...