NF 546

Tocris Bioscience, part of Bio-Techne | Catalog # 3892

Selective P2Y11 agonist
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Key Product Details

Description

Selective P2Y11 agonist

View all P2Y Receptor Agonists »

Product Description

NF 546 is a P2Y11 agonist (pEC50 = 6.27). Exhibits selectivity for P2Y11 over a range of P2Y and P2X receptors. Also inhibits DNA-binding activity of HMGA2 (IC50 = 5.49 μM).

Product Specifications

Molecular Weight

1180.74

Formula

C47H44N6Na4O17P4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4,4'-(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid tetrasodium salt

CAS Number

1006028-37-0

PubChem ID

73755075

InChI Key

GSMUPMANKNAMAS-UHFFFAOYSA-J

SMILES

[Na+].[Na+].[Na+].[Na+].CC1=CC=C(C=C1NC(=O)C1=CC=CC(NC(=O)NC2=CC=CC(=C2)C(=O)NC2=C(C)C=CC(=C2)C(=O)NC2=CC=C(CP(O)([O-])=O)C=C2CP(O)([O-])=O)=C1)C(=O)NC1=C(CP(O)([O-])=O)C=C(CP(O)([O-])=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 11.81 10 with gentle warming

Preparing Stock Solutions for NF 546

The following data is based on the product molecular weight 1180.74

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.47 mL 42.35 mL 84.69 mL
0.5 mM 1.69 mL 8.47 mL 16.94 mL
1 mM 0.85 mL 4.23 mL 8.47 mL
5 mM 0.17 mL 0.85 mL 1.69 mL

Calculators

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Reconstitution Calculator

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Product Documents for NF 546

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NF 546

For research use only

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