Neurodazine
Tocris Bioscience, part of Bio-Techne | Catalog # 3656
Induces neurogenesis in mature skeletal muscle cells
Discontinued Product
3656 has been discontinued.
View all Compounds for Stem Cell Differentiation products.
Key Product Details
Description
Induces neurogenesis in mature skeletal muscle cells
Product Description
Neurodazine is an induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.Product Specifications
Molecular Weight
456.92
Formula
C27H21ClN2O3
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
CAS Number
937807-66-4
PubChem ID
16112820
InChI Key
FEEOFPAEDSMOTO-UHFFFAOYSA-N
SMILES
ClC1=CC=CC(C(O3)=CC=C3C2=NC(C5=CC=C(OC)C=C5)=C(C4=CC=C(OC)C=C4)N2)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.69 | 100 | |
| Ethanol | 22.85 | 50 |
Preparing Stock Solutions
for Neurodazine
The following data is based on the product molecular weight 456.92
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.19 mL | 10.94 mL | 21.89 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
| 10 mM | 0.22 mL | 1.09 mL | 2.19 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.44 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Halder Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons. Chem.Biol. 2015 PMID: 26590637
- Williams Synthetic small molecules that induce neurogenesis in skeletal muscle. J.Am.Chem.Soc. 2007 PMID: 17622149
Product Specific Notices for Neurodazine
For research use only
Loading...
Loading...